| WTA Miami Qual | 03/21 16:50 | 45 | [83] Varvara Lepchenko v Mariana Duque Marino [104] | 4-6,6-1,6-1 | |
| WTA Miami Qual | 03/20 14:00 | 44 | [321] Urszula Radwanska v Mariana Duque Marino [104] | 2-6,2-6 | |
| WTA Indian Wells | 03/11 20:45 | 24 | [9] Madison Keys v Mariana Duque Marino [112] | 6-1,7-5 | |
| WTA Indian Wells | 03/09 19:00 | 23 | [112] Mariana Duque Marino v Patricia Maria Tig [99] | 6-4,0-6,6-4 | |
| WTA Indian Wells Qual | 03/07 19:00 | 45 | [84] Maria Sakkari v Mariana Duque Marino [112] | 6-7,3-6 | |
| WTA Indian Wells Qual | 03/06 21:00 | 44 | Viktoriya Tomova v Mariana Duque Marino | 2-6,2-6 | |
| WTA Acapulco Qual | 02/27 00:25 | 46 | Mariana Duque Marino v Bethanie Mattek-Sands | 0-6,1-6 | |
| WTA Acapulco Qual | 02/26 01:10 | 45 | Mariana Duque Marino v Francoise Abanda | 6-1,6-4 | |
| ITF Women Surprise | 02/18 18:00 | 28 | Caroline Dolehide v Mariana Duque Marino | 6-4,6-1 | |
| ITF Women Surprise | 02/17 17:00 | 27 | Bianca Andreescu v Mariana Duque Marino | 6-2,3-6,5-7 | |
| ITF Women Surprise | 02/16 18:45 | 26 | Chloe Paquet v Mariana Duque Marino | 2-6,2-6 | |
| ITF Women Surprise | 02/15 16:00 | 25 | Megan McCray v Mariana Duque Marino | 0-6,0-6 | |
| 2017 Fed Cup | 02/10 17:10 | 2 | Renata Zarazua v Mariana D. Marino | 2-6,1-6 | |
| 2017 Fed Cup | 02/08 17:15 | 2 | Mariana Duque Marino v Daniela Seguel | 6-4,3-6,6-4 | |
| 2017 Fed Cup | 02/07 17:20 | - | Catalina Pella v Mariana Duque Marino | 1-6,6-3,7-6 | |
| 2017 Fed Cup | 02/06 19:10 | - | Teliana Pereira v Mariana Duque Marino | 4-6,1-6 | |
| Australian Open 2017 Women | 01/16 06:10 | 23 | Mariana Duque Marino v Svetlana Kuznetsova | 0-6,1-6 | |
| US Open 2016 Women | 08/30 20:45 | 23 | Mariana Duque Marino v Jelena Jankovic | 4-6,1-6 | |
| WTA Montreal | 07/27 01:15 | 24 | Dominika Cibulkova v Mariana Duque Marino | 6-2,6-2 | |
| WTA Montreal Qual | 07/24 15:00 | 45 | Mariana Duque Marino v Olga Govortsova | 4-6,7-6,6-1 | |
| Wimbledon - naised | 06/27 10:30 | 23 | Jana Cepelova v Mariana Duque Marino | 7-5,7-5 | |
| WTA Mallorca | 06/17 15:50 | 27 | Anastasija Sevastova v Mariana Duque Marino | 6-4,3-6,6-3 | |
| WTA Mallorca | 06/15 17:00 | 26 | Mariana Duque Marino v Sabine Lisicki | 1-6,6-3,6-4 | |
| WTA Mallorca | 06/13 16:00 | 25 | Alison Van Uytvanck v Mariana Duque Marino | 6-3,3-6,4-6 | |
| Wimbledon - naised | 07/01 16:20 | 24 | Mariana Duque Marino v Andrea Petkovic | 3-6,1-6 | |
| Wimbledon - naised | 06/29 17:25 | 23 | Mariana Duque Marino v Naomi Broady | 7-6,6-3 | |
| WTA Prague Qual | 04/26 09:45 | 46 | Jelena Ostapenko v Mariana Duque Marino | 6-4,7-6 | |
| WTA Prague Qual | 04/25 08:00 | 45 | Katerina Vankova v Mariana Duque Marino | 6-7,3-6 |