| ITF Women Charlottesville | 04/26 17:45 | 26 | [287] Camilla Rosatello v Mariana Duque Marino [112] | 2-6,3-6 | |
| ITF Women Charlottesville | 04/26 13:30 | 25 | [422] Iga Swiatek v Mariana Duque Marino [112] | 6-7,3-6 | |
| ITF Women Dothan | 04/22 14:00 | 29 | [108] Taylor Townsend v Mariana D. Marino [125] | 6-2,2-6,6-1 | |
| ITF Women Dothan | 04/21 16:00 | 28 | [235] Francesca Di Lorenzo v Mariana D. Marino [125] | 2-6,0-6 | |
| ITF Women Dothan | 04/20 16:00 | 27 | [125] Mariana D. Marino v Sofia Kenin [87] | 6-4,6-1 | |
| ITF Women Dothan | 04/19 23:00 | 26 | [125] Mariana D. Marino v Louisa Chirico [245] | 6-2,3-6,7-6 | |
| ITF Women Dothan | 04/18 16:40 | 25 | [125] Mariana D. Marino v Victoria Duval [227] | 5-7,6-3,6-0 | |
| WTA Bogota | 04/11 19:30 | 25 | [123] Mariana Duque Marino v Ana Bogdan [76] | 1-6,6-7 | |
| WTA Monterrey | 04/04 01:45 | 25 | [123] Mariana Duque Marino v Danielle Collins [53] | 1-6,3-6 | |
| WTA Miami Qual | 03/19 23:15 | 44 | [137] Ysaline Bonaventure v Mariana Duque Marino [118] | 6-3,6-2 | |
| WTA Indian Wells Qual | 03/06 00:50 | 44 | Ajla Tomljanovic v Mariana Duque Marino | 6-3,6-0 | |
| ITF Women Sao Paulo | 03/03 17:05 | 28 | Mariana Duque Marino v Tamara Zidansek | 7-5,5-7,2-6 | |
| ITF Women Sao Paulo | 03/02 22:55 | 27 | Mariana Duque Marino v Cindy Burger | Retired | |
| ITF Women Sao Paulo | 03/01 15:15 | 26 | Mariana Duque Marino v Nathaly Kurata | 6-7,6-2,6-2 | |
| ITF Women Sao Paulo | 02/28 14:20 | 25 | Mariana Duque Marino v Camila G Campiz | 6-4,4-6,6-1 | |
| ITF Women Curitiba | 02/24 14:00 | 28 | Mariana Duque Marino v Fiona Ferro | 3-6,3-6 | |
| ITF Women Curitiba | 02/23 14:30 | 27 | Mariana Duque Marino v Audrey Albie | 7-6,3-6,6-3 | |
| ITF Women Curitiba | 02/22 20:30 | 26 | Mariana Duque Marino v Montserrat Gonzalez | 6-2,6-3 | |
| ITF Women Curitiba | 02/20 20:15 | 25 | Mariana Duque Marino v Nathalia Wolf Gasparin | 6-0,6-0 | |
| ITF Women Midland | 01/30 17:15 | 25 | Jessica Pegula v Mariana Duque Marino | 6-2,6-1 | |
| WTA Newport Beach | 01/22 19:15 | 25 | Mariana Duque Marino v Kayla Day | 3-6,6-7 | |
| Austraalia lahtised meistrivõistlused - naised | 01/15 00:00 | 23 | Ying-Ying Duan v Mariana Duque Marino | 6-0,6-1 | |
| WTA Hobart Qual | 01/05 23:00 | 45 | Nina Stojanovic v Mariana Duque Marino | 6-4,6-1 | |
| WTA Seoul | 09/18 03:00 | 25 | [155] Luksika Kumkhum v Mariana Duque Marino [104] | 3-6,6-4,6-1 | |
| US Open Women Qual | 08/25 17:15 | 46 | [107] Mariana Duque Marino v Mihaela Buzarnescu [133] | 7-6,2-6,4-6 | |
| US Open Women Qual | 08/24 18:00 | 45 | Mariana Duque Marino v Alexa Glatch | 6-4,6-3 | |
| US Open Women Qual | 08/22 22:50 | 44 | Mariana Duque Marino v Kathinka Von Deichmann | 7-6,4-6,6-4 | |
| WTA Cincinnati Qual | 08/13 17:30 | 45 | [107] Mariana Duque Marino v Monica Puig [69] | 4-6,7-6,5-7 | |
| WTA Cincinnati Qual | 08/12 17:30 | 44 | [57] Monica Niculescu v Mariana Duque Marino [107] | 6-4,2-6,1-6 | |
| WTA Toronto | 08/07 23:35 | 24 | [40] Katerina Siniakova v Mariana Duque Marino [107] | 4-6,6-0,6-4 |