Head to Head
| NCAAF | 2021/10/16 16:00 | Ohio v Buffalo | W | 26-27 |
| NCAAF | 2019/10/05 19:30 | Ohio v Buffalo | L | 21-20 |
| NCAAF | 2018/11/15 00:00 | Buffalo v Ohio | L | 17-52 |
| NCAAF | 2017/11/24 18:00 | Ohio v Buffalo | W | 24-31 |
| NCAAF | 2016/11/03 22:00 | Buffalo v Ohio | L | 10-34 |
| NCAAF | 2015/10/24 19:30 | Buffalo v Ohio | W | 41-17 |
| NCAAF | 2014/11/06 01:00 | Ohio v Buffalo | L | 37-14 |
| NCAAF | 2012/10/06 12:00 | Ohio v Buffalo | L | 38-31 |
| NCAAF | 2011/10/08 12:00 | Buffalo v Ohio | W | 38-37 |
| NCAAF | 2010/11/04 12:00 | Ohio v Buffalo | L | 34-17 |
| NCAAF | 2009/11/10 12:00 | Buffalo v Ohio | L | 24-27 |
| NCAAF | 2008/10/28 12:00 | Ohio v Buffalo | W | 19-32 |
| NCAAF | 2007/10/06 12:00 | Buffalo v Ohio | W | 31-10 |
| NCAAF | 2006/10/21 12:00 | Ohio v Buffalo | L | 42-7 |
| NCAAF | 2005/10/29 12:00 | Buffalo v Ohio | L | 20-34 |
| NCAAF | 2004/09/25 12:00 | Ohio v Buffalo | L | 34-0 |
| NCAAF | 2003/10/25 12:00 | Buffalo v Ohio | W | 26-17 |
| NCAAF | 2002/09/28 12:00 | Ohio v Buffalo | L | 34-32 |
| NCAAF | 2001/11/03 12:00 | Buffalo v Ohio | W | 44-0 |
| NCAAF | 2000/10/07 12:00 | Ohio v Buffalo | L | 42-20 |