[1] Clemson 31-3 Boston College [9] 2022-10-08 23:30
Stadium: Alumni Stadium Round: 1
Home Manager: Jeff Hafley Away Manager: Dabo Swinney
Head to Head
| NCAAF | 2021/10/02 23:30 | Boston College v Clemson | W | 13-19 |
| NCAAF | 2020/10/31 16:00 | Boston College v Clemson | W | 28-34 |
| NCAAF | 2019/10/26 23:30 | Clemson v Boston College | W | 59-7 |
| NCAAF | 2018/11/11 01:00 | Clemson v Boston College | W | 27-7 |
| NCAAF | 2017/09/23 19:30 | Clemson v Boston College | W | 34-7 |
| NCAAF | 2017/09/23 19:30 | Boston College v Clemson | W | 7-34 |
| NCAAF | 2016/10/07 23:30 | Clemson v Boston College | W | 56-10 |
| NCAAF | 2015/10/17 23:00 | Clemson v Boston College | W | 34-17 |
| NCAAF | 2014/10/18 19:30 | Boston College v Clemson | W | 13-17 |
| NCAAF | 2012/09/29 12:00 | Boston College v Clemson | W | 31-45 |
| NCAAF | 2011/10/08 12:00 | Clemson v Boston College | W | 36-14 |
| NCAAF | 2010/10/30 12:00 | Boston College v Clemson | L | 16-10 |
| NCAAF | 2009/09/19 12:00 | Clemson v Boston College | W | 25-7 |
| NCAAF | 2008/11/01 12:00 | Boston College v Clemson | W | 21-27 |
| NCAAF | 2007/11/17 12:00 | Clemson v Boston College | L | 17-20 |
| NCAAF | 2006/09/09 12:00 | Boston College v Clemson | L | 34-33 |
| NCAAF | 2005/09/24 12:00 | Clemson v Boston College | L | 13-16 |