Stadium: Husky Stadium Round: 1
| NCAAF | 2022/11/19 20:00 | Houston Christian v Tarleton State | L | 7-49 |
| NCAAF | 2022/11/12 20:00 | McNeese State v Houston Christian | L | 21-10 |
| NCAAF | 2022/11/05 19:00 | Houston Christian v Incarnate Word | L | 20-73 |
| NCAAF | 2022/10/29 19:00 | Tennessee Martin v Houston Christian | L | 52-28 |
| NCAAF | 2022/10/22 19:00 | Houston Christian v Texas A&M-Commerce | L | 3-31 |
| NCAAF | 2022/10/15 23:00 | Northwestern State v Houston Christian | L | 37-10 |
| NCAAF | 2022/10/08 23:00 | Nicholls State v Houston Christian | L | 19-17 |
| NCAAF | 2022/10/01 20:00 | Houston Christian v Lamar | W | 37-34 |