[2] Nacional de Football 3-1 Peñarol [8] 2022-09-04 18:30
Stadium: Estadio Gran Parque Central Round: 4
Referee: Andres Matonte Home Manager: Pablo Repetto Away Manager: Leonardo Ramos
Head to Head
| Uruguay Apertura | 2022/02/27 20:00 | Peñarol v Nacional de Football | L | 1-0 |
| Euroopa sõpruskohtumised | 2022/01/26 22:00 | Peñarol v Nacional de Football | L | 1-0 |
| Uruguay Clausura | 2021/10/31 19:00 | Peñarol v Nacional de Football | D | 0-0 |
| Copa Sudamericana | 2021/07/23 00:30 | Peñarol v Nacional de Football | W | 0-1 |
| Copa Sudamericana | 2021/07/16 00:30 | Nacional de Football v Peñarol | L | 1-2 |
| Uruguay Apertura | 2021/07/04 19:00 | Nacional de Football v Peñarol | W | 2-0 |
| Uruguay Clausura | 2021/02/03 21:30 | Peñarol v Nacional de Football | D | 0-0 |
| Uruguay Torneo Intermedio | 2020/12/13 20:30 | Peñarol v Nacional de Football | L | 3-2 |
Home History
| Uruguay Clausura | 2022/08/27 21:30 | Torque v Nacional de Football | W | 0-3 |
| Uruguay Clausura | 2022/08/20 21:00 | Nacional de Football v Montevideo Wanderers | W | 2-0 |
| Uruguay Clausura | 2022/08/14 18:30 | Liverpool Montevideo v Nacional de Football | W | 0-1 |
| Copa Sudamericana | 2022/08/09 22:15 | Atlético GO v Nacional de Football | L | 3-0 |
| Uruguay Clausura | 2022/08/05 23:00 | Nacional de Football v Rentistas | W | 3-0 |
| Copa Sudamericana | 2022/08/02 22:15 | Nacional de Football v Atlético GO | L | 0-1 |
| Uruguay Clausura | 2022/07/30 22:00 | Deportivo Maldonado v Nacional de Football | L | 2-1 |
| Uruguay Torneo Intermedio | 2022/07/27 23:00 | Liverpool Montevideo v Nacional de Football | W | 0-1 |
Away History
| Uruguay Clausura | 2022/08/28 21:00 | Peñarol v Danubio | D | 1-1 |
| Uruguay Clausura | 2022/08/22 22:00 | Deportivo Maldonado v Peñarol | D | 1-1 |
| Uruguay Clausura | 2022/08/13 21:30 | Peñarol v Albion FC | W | 2-0 |
| Uruguay Clausura | 2022/08/07 21:30 | Defensor Sporting v Peñarol | W | 2-3 |
| Uruguay Clausura | 2022/08/01 23:00 | Peñarol v Atlético Fénix Montevideo | L | 0-1 |
| Uruguay Torneo Intermedio | 2022/07/26 22:30 | Peñarol v Rentistas | W | 2-0 |
| Uruguay Torneo Intermedio | 2022/07/23 18:00 | Albion FC v Peñarol | W | 1-3 |
| Uruguay Torneo Intermedio | 2022/07/20 22:00 | Peñarol v Rentistas | W | 2-0 |