Stadium: Fitton Field Round: 1
Home Manager: Bob Chesney Away Manager: Chris Merritt
| NCAAF | 2022/11/05 18:00 | Campbell v Bryant | W | 37-43 |
| NCAAF | 2022/10/29 17:30 | Bryant v Gardner Webb | L | 40-48 |
| NCAAF | 2022/10/15 20:00 | Charleston Southern v Bryant | L | 24-23 |
| NCAAF | 2022/10/08 17:00 | Bryant v Southern Connecticut State | W | 56-10 |
| NCAAF | 2022/10/01 23:00 | Bryant v North Carolina A&T | L | 13-24 |
| NCAAF | 2022/09/24 17:00 | Bryant v LIU Brooklyn | W | 31-29 |
| NCAAF | 2022/09/17 16:30 | Bryant v Brown | L | 38-44 |
| NCAAF | 2022/09/10 22:00 | Rhode Island v Bryant | L | 35-21 |
| NCAAF | 2022/11/05 16:00 | Lehigh v Holy Cross | W | 14-42 |
| NCAAF | 2022/10/29 17:00 | Fordham v Holy Cross | W | 52-53 |
| NCAAF | 2022/10/22 19:30 | Holy Cross v Lafayette | W | 24-21 |
| NCAAF | 2022/10/08 20:00 | Bucknell v Holy Cross | W | 0-57 |
| NCAAF | 2022/10/01 17:00 | Holy Cross v Harvard | W | 30-21 |
| NCAAF | 2022/09/24 17:00 | Holy Cross v Colgate | W | 35-10 |
| NCAAF | 2022/09/17 18:00 | Yale v Holy Cross | W | 14-38 |
| NCAAF | 2022/09/10 22:00 | Holy Cross v Buffalo | W | 37-31 |