[18] Juárez FC 0-2 Mazatlán FC [16] 2022-04-23 02:00
Stadium: Estadio Olimpico Benito Juarez Round: 16
Referee: Oscar Mejia Garcia Home Manager: Ricardo Ferretti Away Manager: Gabriel Caballero
Head to Head
| Mehhiko Liga MX | 2021/09/29 00:00 | Mazatlán FC v Juárez FC | L | 3-1 |
| Mehhiko Liga MX | 2021/02/20 03:30 | Juárez FC v Mazatlán FC | W | 1-0 |
| Mehhiko Liga MX | 2020/10/17 02:30 | Mazatlán FC v Juárez FC | L | 3-2 |
Home History
| Mehhiko Liga MX | 2022/04/20 02:00 | Toluca v Juárez FC | W | 0-1 |
| Mehhiko Liga MX | 2022/04/16 02:00 | Juárez FC v Pachuca | L | 1-2 |
| Mehhiko Liga MX | 2022/04/10 02:00 | Club América v Juárez FC | L | 3-0 |
| Mehhiko Liga MX | 2022/04/03 03:00 | Juárez FC v Unam Pumas | L | 0-1 |
| Mehhiko Liga MX | 2022/03/21 03:06 | Tijuana v Juárez FC | L | 1-0 |
| Mehhiko Liga MX | 2022/03/16 03:06 | Monterrey v Juárez FC | L | 3-0 |
| Mehhiko Liga MX | 2022/03/12 03:00 | Juárez FC v Atlas | L | 1-2 |
| Mehhiko Liga MX | 2022/03/05 03:00 | Juárez FC v Leon | L | 0-1 |
Away History
| Mehhiko Liga MX | 2022/04/20 02:00 | Mazatlán FC v Santos Laguna | W | 1-0 |
| Mehhiko Liga MX | 2022/04/15 02:00 | Atlas v Mazatlán FC | W | 1-2 |
| Mehhiko Liga MX | 2022/04/09 02:00 | Mazatlán FC v Cruz Azul | D | 1-1 |
| Mehhiko Liga MX | 2022/04/02 02:00 | Atlético San Luis v Mazatlán FC | L | 1-0 |
| Mehhiko Liga MX | 2022/03/26 23:00 | Unam Pumas v Mazatlán FC | D | 1-1 |
| Mehhiko Liga MX | 2022/03/21 03:00 | Mazatlán FC v Leon | L | 1-2 |
| Mehhiko Liga MX | 2022/03/12 03:06 | Monterrey v Mazatlán FC | L | 2-1 |
| Mehhiko Liga MX | 2022/03/02 03:00 | Mazatlán FC v Necaxa | D | 0-0 |