[3] ANA Ducks 2-0 BUF Sabres [6] 2021-12-08 00:30
Stadium: KeyBank Center
Home Manager: Don Granato Away Manager: Dallas Eakins
Head to Head
| NHL | 2021/10/29 02:00 | BUF Sabres v ANA Ducks | L | 4-3 |
| NHL | 2020/02/09 20:00 | ANA Ducks v BUF Sabres | W | 3-2 |
| NHL | 2019/10/17 02:00 | BUF Sabres v ANA Ducks | W | 2-5 |
| NHL | 2018/12/23 00:00 | ANA Ducks v BUF Sabres | L | 0-3 |
| NHL | 2018/10/22 00:00 | BUF Sabres v ANA Ducks | L | 4-2 |
| NHL | 2018/02/07 00:00 | ANA Ducks v BUF Sabres | W | 4-3 |
| NHL | 2017/10/16 01:00 | BUF Sabres v ANA Ducks | L | 3-1 |
| NHL | 2017/03/18 04:33 | BUF Sabres v ANA Ducks | D | 2-2 |
Home History
| NHL | 2021/12/07 00:00 | ANA Ducks v WAS Capitals | L | 3-4 |
| NHL | 2021/12/04 03:00 | CAL Flames v ANA Ducks | L | 4-3 |
| NHL | 2021/12/02 03:00 | VGS Golden Knights v ANA Ducks | W | 5-6 |
| NHL | 2021/12/01 03:30 | ANA Ducks v LA Kings | W | 5-4 |
| NHL | 2021/11/29 01:00 | TOR Maple Leafs v ANA Ducks | L | 5-1 |
| NHL | 2021/11/26 21:00 | OTT Senators v ANA Ducks | W | 0-4 |
| NHL | 2021/11/25 02:00 | ANA Ducks v COL Avalanche | L | 2-5 |
| NHL | 2021/11/23 01:00 | ANA Ducks v NAS Predators | L | 2-3 |
Away History
| NHL | 2021/12/05 00:30 | BUF Sabres v CAR Hurricanes | L | 2-6 |
| NHL | 2021/12/03 00:00 | BUF Sabres v FLA Panthers | L | 4-7 |
| NHL | 2021/11/30 00:00 | SEA Kraken v BUF Sabres | L | 7-4 |
| NHL | 2021/11/28 00:00 | BUF Sabres v DET Red Wings | L | 2-3 |
| NHL | 2021/11/27 00:00 | MON Canadiens v BUF Sabres | W | 1-4 |
| NHL | 2021/11/25 00:00 | BOS Bruins v BUF Sabres | L | 5-1 |
| NHL | 2021/11/23 00:00 | CLB Blue Jackets v BUF Sabres | L | 7-4 |
| NHL | 2021/11/21 23:00 | BUF Sabres v NY Rangers | L | 4-5 |