[5] Wake Forest 55-58 North Carolina [70] 2021-11-06 16:00
Stadium: Kenan Stadium Round: 1
Home Manager: Mack Brown Away Manager: Dave Clawson
Head to Head
| NCAAF | 2020/11/14 17:00 | Wake Forest v North Carolina | L | 53-59 |
| NCAAF | 2019/09/13 22:00 | North Carolina v Wake Forest | W | 18-24 |
| NCAAF | 2015/10/17 23:00 | North Carolina v Wake Forest | L | 50-14 |
| NCAAF | 2012/09/08 12:00 | Wake Forest v North Carolina | W | 28-27 |
| NCAAF | 2011/10/29 12:00 | North Carolina v Wake Forest | L | 49-24 |
| NCAAF | 2007/10/27 12:00 | Wake Forest v North Carolina | W | 37-10 |
| NCAAF | 2004/11/13 12:00 | Wake Forest v North Carolina | L | 24-31 |
| NCAAF | 2003/11/08 12:00 | North Carolina v Wake Forest | L | 42-34 |
Home History
| NCAAF | 2021/10/30 20:00 | Duke v Wake Forest | W | 7-45 |
| NCAAF | 2021/10/23 16:00 | Wake Forest v Army | W | 70-56 |
| NCAAF | 2021/10/09 19:30 | Wake Forest v Syracuse | W | 40-37 |
| NCAAF | 2021/10/02 16:30 | Louisville v Wake Forest | W | 34-37 |
| NCAAF | 2021/09/24 23:00 | Wake Forest v Virginia | W | 37-17 |
| NCAAF | 2021/09/18 19:30 | Florida State v Wake Forest | W | 14-35 |
| NCAAF | 2021/09/11 16:00 | Norfolk State v Wake Forest | W | 16-41 |
| NCAAF | 2021/09/03 23:00 | Old Dominion v Wake Forest | W | 10-42 |
Away History
| NCAAF | 2021/10/30 23:30 | North Carolina v Notre Dame | L | 34-44 |
| NCAAF | 2021/10/16 19:30 | Miami Florida v North Carolina | W | 42-45 |
| NCAAF | 2021/10/09 19:30 | Florida State v North Carolina | L | 35-25 |
| NCAAF | 2021/10/02 16:00 | Duke v North Carolina | W | 7-38 |
| NCAAF | 2021/09/25 23:30 | North Carolina v Georgia Tech | L | 22-45 |
| NCAAF | 2021/09/18 23:30 | Virginia v North Carolina | W | 39-59 |
| NCAAF | 2021/09/11 23:30 | Georgia State v North Carolina | W | 17-59 |
| NCAAF | 2021/09/03 22:00 | North Carolina v Virginia Tech | L | 10-17 |