[119] Wofford 14-34 North Carolina [66] 2021-11-20 17:00
Stadium: Kenan Stadium Round: 1
Home Manager: Mack Brown Away Manager: Josh Conklin
Home History
| NCAAF | 2021/11/13 19:00 | Wofford v The Citadel | L | 44-45 |
| NCAAF | 2021/11/06 17:30 | Tennessee Chattanooga v Wofford | L | 35-10 |
| NCAAF | 2021/10/30 17:30 | Western Carolina v Wofford | L | 41-21 |
| NCAAF | 2021/10/23 22:00 | Wofford v Mercer | L | 14-45 |
| NCAAF | 2021/10/16 17:30 | Samford v Wofford | L | 27-24 |
| NCAAF | 2021/10/09 17:30 | Furman v Wofford | L | 42-20 |
| NCAAF | 2021/10/02 19:30 | Wofford v East Tennessee State | L | 21-27 |
| NCAAF | 2021/09/25 17:30 | Wofford v VMI | L | 23-31 |
Away History
| NCAAF | 2021/11/12 00:30 | North Carolina v Pittsburgh | L | 23-30 |
| NCAAF | 2021/11/06 16:00 | Wake Forest v North Carolina | W | 55-58 |
| NCAAF | 2021/10/30 23:30 | North Carolina v Notre Dame | L | 34-44 |
| NCAAF | 2021/10/16 19:30 | Miami Florida v North Carolina | W | 42-45 |
| NCAAF | 2021/10/09 19:30 | Florida State v North Carolina | L | 35-25 |
| NCAAF | 2021/10/02 16:00 | Duke v North Carolina | W | 7-38 |
| NCAAF | 2021/09/25 23:30 | North Carolina v Georgia Tech | L | 22-45 |
| NCAAF | 2021/09/18 23:30 | Virginia v North Carolina | W | 39-59 |