IND Colts 27-17 Detroit Lions 2021-08-27 23:00
Stadium: Ford Field
Home Manager: Dan Campbell Away Manager: Frank Reich
Head to Head
| NFL | 2020/11/01 18:00 | IND Colts v Detroit Lions | W | 41-21 |
| NFLi eelhooaeg | 2017/08/13 17:30 | Detroit Lions v IND Colts | L | 24-10 |
| NFL | 2016/09/11 20:25 | Detroit Lions v IND Colts | L | 39-35 |
Home History
| NFLi eelhooaeg | 2021/08/22 00:00 | IND Colts v MIN Vikings | W | 12-10 |
| NFLi eelhooaeg | 2021/08/15 17:00 | CAR Panthers v IND Colts | W | 18-21 |
| NFL | 2021/01/09 18:05 | IND Colts v Buffalo Bills | L | 24-27 |
| NFL | 2021/01/03 21:25 | JAX Jaguars v IND Colts | W | 14-28 |
| NFL | 2020/12/27 18:00 | IND Colts v PIT Steelers | L | 24-28 |
| NFL | 2020/12/20 18:00 | Houston Texans v IND Colts | W | 20-27 |
| NFL | 2020/12/13 21:05 | IND Colts v LV Raiders | W | 44-27 |
| NFL | 2020/12/06 18:00 | IND Colts v Houston Texans | W | 26-20 |
Away History
| NFLi eelhooaeg | 2021/08/21 23:30 | Detroit Lions v PIT Steelers | L | 20-26 |
| NFLi eelhooaeg | 2021/08/13 23:00 | Buffalo Bills v Detroit Lions | L | 16-15 |
| NFL | 2021/01/03 18:00 | MIN Vikings v Detroit Lions | L | 37-35 |
| NFL | 2020/12/26 18:00 | TB Buccaneers v Detroit Lions | L | 47-7 |
| NFL | 2020/12/20 18:00 | Detroit Lions v TEN Titans | L | 25-46 |
| NFL | 2020/12/13 21:25 | GB Packers v Detroit Lions | L | 31-24 |
| NFL | 2020/12/06 18:00 | Detroit Lions v Chicago Bears | W | 34-30 |
| NFL | 2020/11/26 17:30 | Houston Texans v Detroit Lions | L | 41-25 |