[3] Corinthians 4-0 River Plate Asunción [2] 2021-05-27 00:30
Stadium: Neo Quimica Arena Round: 6
Referee: Jose Ramon Argote Vega Home Manager: Sylvio Mendes Campos Junior Away Manager: Celso Rafael Ayala Gavilan
Head to Head
| Copa Sudamericana | 2021/04/23 00:30 | River Plate Asunción v Corinthians | D | 0-0 |
Home History
| Copa Sudamericana | 2021/05/21 00:30 | Corinthians v Sport Huancayo | W | 5-0 |
| Brasiilia Campeonato Paulista | 2021/05/16 19:00 | Corinthians v Palmeiras | L | 0-2 |
| Copa Sudamericana | 2021/05/14 00:30 | Peñarol v Corinthians | L | 4-0 |
| Brasiilia Campeonato Paulista | 2021/05/11 19:00 | Corinthians v Inter de Limeira | W | 4-1 |
| Brasiilia Campeonato Paulista | 2021/05/09 19:00 | Corinthians v Grêmio Novorizontino | W | 2-1 |
| Copa Sudamericana | 2021/05/07 00:30 | Sport Huancayo v Corinthians | W | 0-3 |
| Brasiilia Campeonato Paulista | 2021/05/03 01:15 | Corinthians v São Paulo | D | 2-2 |
| Copa Sudamericana | 2021/04/29 22:15 | Corinthians v Peñarol | L | 0-2 |
Away History
| Paraguay División Profesional | 2021/05/24 00:00 | Nacional Asunción v River Plate Asunción | W | 0-1 |
| Copa Sudamericana | 2021/05/18 22:15 | River Plate Asunción v Peñarol | W | 2-1 |
| Paraguay División Profesional | 2021/05/16 21:45 | River Plate Asunción v Cerro Porteño | D | 1-1 |
| Copa Sudamericana | 2021/05/14 00:30 | River Plate Asunción v Sport Huancayo | W | 2-1 |
| Paraguay División Profesional | 2021/05/10 00:00 | Guairena FC v River Plate Asunción | D | 0-0 |
| Copa Sudamericana | 2021/05/07 00:30 | Peñarol v River Plate Asunción | L | 3-0 |
| Paraguay División Profesional | 2021/05/03 23:00 | River Plate Asunción v Libertad Asunción | L | 1-3 |
| Copa Sudamericana | 2021/04/29 22:15 | Sport Huancayo v River Plate Asunción | W | 1-2 |