[3] River Plate Asunción 2-1 Sport Huancayo [4] 2021-05-14 00:30
Stadium: Estadio Defensores del Chaco Round: 4
Referee: Angelo Hermosilla Home Manager: Celso Rafael Ayala Gavilan Away Manager: Wilmar Valencia
Head to Head
| Copa Sudamericana | 2021/04/29 22:15 | Sport Huancayo v River Plate Asunción | W | 1-2 |
Home History
| Paraguay División Profesional | 2021/05/10 00:00 | Guairena FC v River Plate Asunción | D | 0-0 |
| Copa Sudamericana | 2021/05/07 00:30 | Peñarol v River Plate Asunción | L | 3-0 |
| Paraguay División Profesional | 2021/05/03 23:00 | River Plate Asunción v Libertad Asunción | L | 1-3 |
| Copa Sudamericana | 2021/04/29 22:15 | Sport Huancayo v River Plate Asunción | W | 1-2 |
| Paraguay División Profesional | 2021/04/26 22:15 | Sportivo Luqueño v River Plate Asunción | D | 2-2 |
| Copa Sudamericana | 2021/04/23 00:30 | River Plate Asunción v Corinthians | D | 0-0 |
| Paraguay División Profesional | 2021/04/18 00:00 | River Plate Asunción v Sol de América | L | 0-2 |
| Paraguay División Profesional | 2021/04/12 23:00 | Guaraní Asunción v River Plate Asunción | L | 2-0 |
Away History
| Peruu Liga 1 | 2021/05/09 20:30 | Sport Huancayo v Cesar Vallejo | D | 0-0 |
| Copa Sudamericana | 2021/05/07 00:30 | Sport Huancayo v Corinthians | L | 0-3 |
| Peruu Liga 1 | 2021/05/03 16:00 | Sport Huancayo v Alianza Universidad | D | 3-3 |
| Copa Sudamericana | 2021/04/29 22:15 | Sport Huancayo v River Plate Asunción | L | 1-2 |
| Peruu Liga 1 | 2021/04/26 20:30 | Cusco FC v Sport Huancayo | W | 0-1 |
| Copa Sudamericana | 2021/04/23 00:30 | Peñarol v Sport Huancayo | L | 5-1 |
| Peruu Liga 1 | 2021/04/14 20:30 | Sport Huancayo v Alianza Lima | D | 0-0 |
| Copa Sudamericana | 2021/04/08 00:30 | Sport Huancayo v UTC Cajamarca | W | 4-0 |